Sections or subsections omitted from the full prescribing information are not listed. FULL PRESCRIBING INFORMATION: CONTENTS * 1 INDICATIONS AND USAGE 1.1 Hypertension 2 DOSAGE AND ADMINISTRATION 2.1 Hypertension 2.2 Subpopulations 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Abrupt Cessation of Therapy 5.2 Angina and Acute Myocardial Infarction 5.3 Bronchospastic Diseases 5.4 Anesthesia and Major Surgery 5.5 Diabetes and Hypoglycemia 5.6 Thyrotoxicosis 5.7 Peripheral Vascular Disease 5.8 Non-dihydropyridine Calcium Channel Blockers 5.9 Use with CYP2D6 Inhibitors 5.10 Impaired Renal Function 5.11 Impaired Hepatic Function 5.12 Risk of Anaphylactic Reactions 5.13 Pheochromocytoma 6 ADVERSE REACTIONS 6.1 Clinical Studies Experience 6.2 Laboratory Abnormalities 6.3 Postmarketing Experience 7 DRUG INTERACTIONS 7.1 CYP2D6 Inhibitors 7.2 Hypotensive Agents 7.3 Digitalis Glycosides 7.4 Calcium Channel Blockers 8 USE IN SPECIFIC POPULATIONS 8.1 Pregnancy 8.2 Lactation 8.4 Pediatric Use 8.5 Geriatric Use 8.6 Heart Failure 10 OVERDOSAGE 11 DESCRIPTION 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action 12.3 Pharmacokinetics 12.4 Pharmacokinetics in Special Populations 12.5 Drug-Drug Interactions 13 NONCLINICAL TOXICOLOGY 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility 14 CLINICAL STUDIES 14.1 Hypertension 16 HOW SUPPLIED/STORAGE AND HANDLING 17 PATIENT COUNSELING INFORMATION
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